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This is Scientific American's 60-second Science, I'm Susanne Bard.
Blood donations save lives. But blood can only be stored under refrigeration for up to six weeks.
After that, it's no longer usable for transfusions.
"Because of that limitation, people have to continually donate blood to meet the needs.
But also, in places where refrigeration may not be available, that can also be a challenge.
It's difficult to have blood available when needed."
University of Louisville bioengineer Jonathan Kopechek.
He says disruptions to regular blood donations due to COVID-19 have put stress on the blood supply,
and the pandemic underscores the need for more reliable long-term storage methods.
Blood can be frozen for extended periods of time...
"But it's pretty rare because of all the challenges and complexities with that process."
Instead Kopechek's team has developed a method of preserving blood so it can be stored in a dehydrated state at room temperature.
To do so, they turned to an unusual preservative: a sugar called trehalose, which is a common ingredient in donuts...
"To help make them look fresh even when they might be months old, and you wouldn't know the difference."
The researchers chose trehalose because, in nature, it's made by hardy animals like tardigrades and sea monkeys―aka brine shrimp―
famous for their ability to survive dehydration.
"So these animals can dry out completely for a long period of time and then be rehydrated and resume normal function.
这里是科学美国人――60秒科学系列,我是苏珊娜・巴德。
献血可以挽救生命。但是血液最多只能冷藏保存6周。
之后,就无法再用于输血。
“因为这个限制,人们必须不断献血以满足需求。
但在可能没有冷藏的地方,这也是个挑战。
在有需要时很难有血液供应。”
路易斯维尔大学的生物工程师乔纳森・科佩奇说到。
他表示,新冠肺炎导致的定期献血中断,给血液供应带来了压力,
而且这场疫情凸显出人们对更可靠的长期储存方法的需求。
血液可以长时间冷冻……
“但这非常罕见,因为这一过程存在种种挑战和复杂问题。”
相反,科佩奇的研究团队开发出一种保存血液的方法,使其可以在室温下以脱水状态保存。
为此,他们找到了一种不同寻常的防腐剂:海藻糖,这种糖是甜甜圈中的常见配料……
“这种糖有助于让甜甜圈看起来很新鲜,即使已经是几个月以前的甜甜圈,你也不会知道有何区别。”
研究人员选择海藻糖是的原因是,它来自自然界中沙蜥蜴和海猴(又称卤虫)等坚韧动物,
它们都以脱水生存能力而闻名。
“因此,这些动物可以完全脱水相当长一段时间,还能再水合并恢复正常功能。
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